Oxidative stress has continued to play major roles in the etiology of many metabolic diseases, diabetes and obesity inclusive. The study on oxidative stress in diabetic obese patients was carried out with patients from two tertiary hospitals in Abia State Nigeria who gave their consent to participate in the study. A total of 120 patients 18 years and above who...
Showing posts with label Biochemistry. Show all posts
Showing posts with label Biochemistry. Show all posts
Saturday, 9 October 2021
Sunday, 19 September 2021
Irregularity of Glycogen Synthase Homeostasis Complications Hepatic and Neuro Defects
Team IJTSRD
September 19, 2021
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Glucose homeostasis is strongly regulated to meet the strength needs of major organs and to maintain human health. The liver has a major role in control glucose homeostasis by controlling numerous pathways of glucose metabolism, over eating collection of glycogen union glycogenesis, separate glycogen of glycogenolysis, glucose separate of glycolysis, and under...
Thursday, 26 August 2021
Comparative Studies of Diabetes in Adult Nigerians Lipid Profile and Antioxidants Vitamins A and C
Team IJTSRD
August 26, 2021
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The study sought to determine the extent to which the usage of social media in the marketing of agricultural products in South West Nigeria can enhance farmers turnover. It employed the survey research design to collect data with the help of a structured questionnaire to elicit information from respondents selected from six 6 south western states. Research data...
Tuesday, 20 July 2021
Identification of Bioactive Phytochemicals using GC–MS in Leaf Ethanolic Extract of Tragia Involucrata L
Team IJTSRD
July 20, 2021
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Tragia involucrata is belonging to the family Euphorbiaceae common medicinal herb in Southern India. In the present investigation, air died powdered ethanol extracts of Tragia involucrata leaf sample was analyzed by gas chromatography mass spectrometry GC–MS to identify the important phytochemical constituents. The GC MS analysis has shown the presence of 43...
Thursday, 30 July 2020
GC–MS Analysis of Bioactive Compounds Present in Ethanol Extract of Panicum Maximum Jacq Leaves
Team IJTSRD
July 30, 2020
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hytoconstituents present in the ethanolic extract of Panicum maximum leaves were explored by Gas Chromatography Mass Spectrometry analysis. The compounds were identified by the gas chromatography coupled with the mass spectrometry. The molecular weight and structure of the compounds of Panicum maximum leaves were ascertained by interpretation of the spectrum...
Friday, 22 May 2020
Endothelial Nitric Oxide Synthase T786C Gene Polymorphism TT Genotype is Associated with High Nitric Oxide Levels and Low HOMA IR Levels in Coronary Artery Disease Patients
Team IJTSRD
May 22, 2020
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BACKGROUND Data suggest eNOS 786T C gene polymorphism is distinct in specific population group, ethnicity and geographic region and perhaps this genetic variability might produce different results on exposure to various environmental factors 9 14. Besides there is hardly any data available in Indian population. Sofurther research is needed to explore the...
Thursday, 21 May 2020
Role of Pre Therapeutic Expression of Human Organic Cation Transporter1 SLC22A1 Gene in Predicting Clinical Outcome in Imatinib Treated CP CML Patients
Team IJTSRD
May 21, 2020
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Background Human organic cation transporter1 hOCT1, SLC22A1 , an influx transporter,is responsible for the uptake of Imatinib into chronic myelod leukemia CML cells. Some patients fail to achieve optimal molecular response to Imatinib, defined as major molecular response MMR i.e.BCR ABL 1 = 0.1 within 12 months of therapy. Pretherapeutic expression of hOCT1...
Tuesday, 10 March 2020
Heavy Metals Level Evaluation in Lycopersicon Esculentum Tomato and Daucus Carota Carrot Cultivated In Two Farming Communities in Kazaure Local Government Area
Team IJTSRD
March 10, 2020
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The exposure to heavy metals such as Ni, Cd, Cr, Co, Pb, As, Hg, Zn, Fe and Cu, has been reported as a risk to human health through the consumption of vegetable when exposed to air pollution and other environmental and agricultural pesticides. This paper is aimed to evaluate the level of heavy metal in carrot and tomatoes cultivated in two farming communities...
Wednesday, 27 November 2019
GC/MS Analysis and Evaluation of Antimicrobial Performance of Aframomum Latifolium Leaf Essential Oil from South West Nigeria
Team IJTSRD
November 27, 2019
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This study was conducted to analyze the chemical constituent and to evaluate the antimicrobial properties of the leaf essential oil of Aframomum latifolium. The leaves of this plant was subjected for hydro distillation using all glass Clevenger apparatus. The volatile oil obtained was analysed by means of gas chromatography mass spectrometry GC Ms . The...
Tuesday, 1 October 2019
Comparative Study of Free Radical Scavenging and Lipid Peroxidation Inhibition Potentials of Oxythenanthera Abyssinica Rhizomes Sourced from South Eastern Nigeria
Team IJTSRD
October 01, 2019
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Oxytenanthera abyssinica rhizomes have been used in the treatment of aliments varying from colics, diabetes, polyuria and albuminiura, these ethanomedicinal potencies have been attributed to its rich phytochemical contents and free radical scavenging capacity. This work is aimed at investigating the effect of crude oil pollution on total phenolic, flavonoids...
Tuesday, 16 July 2019
Effect of crude oil pollution on phytochemical and anti diabetic potentials of Oxytenanthera abyssinica rhizomes in normal and alloxan induced diabetic rats
Team IJTSRD
July 16, 2019
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Objectives This study is aimed at investigating the effect of crude oil pollution on the phytochemical content and anti diabetic potentials of Oxytenanthera abyssinica rhizomes in normal and alloxan induced diabetic rats using standard methods. Method The ability of the extracts to reduce blood glucose level in normal rats was done using 200 and 400 mg kg...
Tuesday, 16 April 2019
Critical Analysis of Wheat Bran as Therapeutic Source
Team IJTSRD
April 16, 2019
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Increasing population now a days is one of the most crucial phases of upcoming future troubles. Food wastage along with the nutritional expenditure should not be entertained. Several milling by products of crops viz., wheat bran, are principle pool of nutrients. It is very much essential to study and gain knowledge about the nutrients, anti oxidants, anti...
Thursday, 4 April 2019
Study of Glutathione Peroxidase GPX Activity Among Betel Quid Chewers of Indian Population
Team IJTSRD
April 04, 2019
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Introduction Betel quid BQ chewing, a habit practiced in Eastern and North Eastern part of India, has known to be associated with cancer of the oral or buccal cavity. BQ is also one of the common mood elevating substances among Indian population. The BQ is a mixture of areca nut Areca catechu, catechu Acacia catechu and slaked lime calcium oxide and calcium...
Wednesday, 10 October 2018
Effect of Methanol Leaf Extract of Vitex Doniana on Cadmium Chloride-Induced Toxicity in Kidney and Liver Tissues of Male Wistar Rats
The aim of this study was to investigate the effects of methanol leaf extract of Vitex doniana MEVd on Cadmium chloride - induced toxicity in the liver and kidney of male Wistar rats was investigated. Twenty five male Wistar rats weighing 171.87 ± 7.86g were acclimatized for two weeks and subsequently randomized into five groups Group 1 rats were administered...
Wednesday, 1 August 2018
Prunin Production From Orange Peel Naringin Hydrolyzed By a-L-rhamnosidase from Aspergillus Flavipus MTCC- 4644
An orange (Citrus sinensis) is the most common fruits in the world. The wastes generated from the orange fruit needs to be put in to beneficial use. In this study the primary wastes (peel) of orange is use for preparation of prunin. a-L-Rhamnosidase (EC 3.2.1.40) secreted by Aspergillus flavipus MTCC-4644 are potential catalysis in hydrolysis of naringin...
Tuesday, 1 May 2018
Biochemical Parameters of Blood Cows at Hight and Low Temperatures
Biochemical analysis of blood is a complex laboratory diagnosis conducted to assess the condition of internal organs and systems and to identify the body's need for microelements and the level of its satisfaction. According to the biochemical parameters of the blood composition, primary diagnostics of the functioning of the liver, kidneys, pancreas and other...
Thursday, 4 January 2018
Clinical Applications of Metabolomics in Diabetes Research
Diabetes mellitus is a multi-factorial disorder related to a dysregulated metabolism. a holistic technique emphasizing each of the person factors with regards to finish pathophysiology of the disease is vital to our information of this heterogeneous disorder.numerous technical advances inside the area of purposeful genomics which include metabolomics and proteomics...
Friday, 3 November 2017
A study on antioxidants (vitamin c & e) in cannabis user in diabetic and non-diabetic subjects
Aim & Objectives: The correlation of Cannabis user groups with duration of one-month, one-year and five year (Both diabetic and non-diabetic groups) with serum Vitamin C level and serum vitamin E level.Research Design and Methods: In a cross-sectional, case-control study, we studied cannabis user 55 and 50 cannabis non-user, male-subjects aged between 25...
Sunday, 21 February 2016
Pharmacological Applications of Isorhamnetin: A Short Review
Isorhamnetin (30-Methoxy-3, 40, 5, 7-tetrahydroxyflavone) is a flavonol, and it belongs to a group of plant secondary metabolites known as flavonoids. It is present in man's daily diet and is known for its biological activities such as antioxidant, antiviral, anticancer, antimicrobial, and anti-inflammatory effects. Isorhamnetin has been reported for its antioxidant...
