International Journal of Trend in Scientific Research and Development

Genus Prunus is peach, plum, apricot, almond like cherry delicious among temperate fruit crops, important because it contains edible, drupe and stone fruits with ornamental value as well. Genus mostly spreads in the temperate regions of the Northern Hemisphere, such as northern Asia, North America and Europe. Species which have global economic importance, harvested or grown from the wild for timber and medicinal purposes. The use of these species, which have been used in folk medicine for many years, differs from country to country and plant cover. Main species used for traditional medical purposes are Prunus americana, Prunus armeniaca, Prunus avium, Prunus cerasus, Prunus dulcis, Prunus ceracifera, Prunus cerasoides, Prunus domestica, Prunus mahaleb, Prunus mume, Prunus persica, Prunus salicina, etc. When the studies are examined, it is seen that there are many in vivo, in vitro and clinical studies that carried out the different biological effects of the extracts obtained from different parts of these species. The literature presented here may suggest new inputs for further biological activity studies and reveal the relationship between traditional use and existing scientific studies. 

Turmeric is a traditional medicinal plant which Containing verity of active ingredients. Chemical constituents of various parts of turmeric plant Curcuma longa L. are extensively investigated. Today's date , at least 235 chemical constituent and their derivative compounds are studied those mainly contains, primarily phenolic compounds and terpenoids have been identified from the species, including phenylpropene, diarylheptanoids, diarylpentanoids with other phenolic compounds, monoterpenes, sesquiterpenes, diterpenes, triterpenoids, sterols, alkaloids, and other compounds. Curcuminoids diarylheptanoids and essential oils are most bioactive chemical components showing various bioactivities in in vitro and in vivo bioassays. The present paper reviews the Introduction, Uses and chemical constituents of this plant. 

Annona squamosa L is a multipurpose tree with edible fruits and is a source of the medicinal and industrial products. It is used as an antioxidant, antidiabetics, hepatoprotective, cytotoxic, genetoxic, anti tumor, anti lice agent etc.Annona squamosa L belongs to the family Annonaceae commonly known as custard apple. Antimicrobial activity of combined methanolic leaf and seed extract of A.squamosa were evaluated against four bacteria Bacillus subtilis, Styphaloccocus aureus gram positive and E.coli, Pseudomonas aerogenosa by using cup and plate method. Maximum inhibition was found with 20mg ml concentration of combined extract as compare to separate leaf and seed extract against all the tested organism under investigation. The study suggest that maximum antibacterial activity was observed against gram negative organism i.e., E.coli and P.aerogenosa. 

The current work aimed to formulate a stable w o cream containing Glycyrrhiza glabra extract and studying its effects on skin pigment. Glycyrrhiza glabra Extract obtained by concentrating the alcoholic extract of Glycyrrhiza glabra roots was entrapped in the inner aqueous phase of W O emulsion. Base containing no active material and a formulation containing ethanolic extract of Glycyrrhiza glabra 1 were prepared. Samples of base and formulation were stored at different accelerated conditions 8°C, 25°C, 40°C, 40°C 75 RH for four weeks to predict the stability of creams. Base and formulation were stable at all accelerated conditions regarding color, liquefaction and phase separation. Both creams were good for sensory evaluation. 

The Aloe Vera plant has been known and utilized for centuries for its wellbeing, magnificence, therapeutic and skin care properties. There are over300 species of aloe, which develops basically within the dry districts of Africa, Asia, Europe and America. Aloe Vera could be a characteristic item thats presently a day regularly utilized within the field of cosmetology. In spite of the fact that there are different signs for its utilize, controlled trials are required to decide its genuine viability. The aloe Vera plant, its properties, component of activity and clinical employments are briefly looked into in this article. The Aloe plant is utilized as a dietary supplement in an assortment of nourishments and as an fixing in restorative items. The far reaching human introduction and its potential harmful and carcinogenic exercises raise security concerns. Chemical examination uncovers that the Aloe plant contains different polysaccharides and phenolic chemicals, outstandingly anthraquinones. Ingestion of Aloe arrangements is related with the runs, hypokalemia, pseudomelanosis coli, kidney disappointment. Aloe Vera can be utilized in different conditions like Gentle to direct burns, Erythema, Genital herpes, Seborrheic dermatitis, Psoriasis vulgaris, Skin moisturizer, Sort 2 diabetes, Verbal lichen planus diseases, Angina pectoris, Ulcerative colitis, UV induced erythema, Kidney stones and Alveolar osteitis. In common, topical application of aloe Vera arrangements has been respected as secure as evaluated by the Corrective Fixing Audit Master Board. Be that as it may, a few case reports of the advancement of touchiness responses and contact dermatitis in reaction to topically connected aloe gel arrangements have been distributed. 

Nanotechnology is a positive concept which will soon improved the field of medical science and technology. In this process used nano meters to penetrate and has improved the medicine and avenues of science. The various types of eye diseases will treated by this nanotechnology, and also enhance the positive effect of the medicated dose. Various aspect of treatment and diagnosis in eye disease are expected to be in future. It will not improved our approach to current therapeutic challenges, but enable to address currently unsolved problems Nanotechnology is the conducted to special treatment process to minimized the drug adverse effect and their accurate dosage form. The technology is being explore as a means of drug delivery, not only the systemic medication, but also for ocular application as many of the condition. 

The media and hormone composition has been standardization and optimization from petiolate explants of Pogostemon Cablin Benth. a medicinally important plant species belonging to the family Lamiaceae. Axillary shoot bud proliferation was initiated from nodel explants cultured on Full MS, ½ MS and ¾ MS medium supplemented with various concentrations of 6 Benzylaminopurine BAP , Indol 3 acetic acid IAA in mg l. The small shoot started appearing with in 7 to 10 days in all cultured bottles, growth was found in Full MS 0.6 mg lit BAP 0.12 mg lit IAA. For Shoot Multiplication, MS supplemented with Full MS 1.5 ml lit BAP 0.3 ml IAA after 30 days of incubation the average shoot length recorded in the medium was found to be 1.79cm and 1.19 respectively. And For Root Induction Full MS, ½ MS, and ¾ MS supplemented medium with three different concentration of IAA and IBA was used the frequency of root formation response was different in all media, best root formation response was obtained in rooting media AR I having concentration Full MS 0.5 ml lit IAA 1 ml lit IBA average no of plant showing root formation were 3.5 in rooting media. About 24 rooted plantlets were selected for transfer in primary hardening. This ex agar plant was transferred to green house for optimizing the physiological condition. Plant were planted in pro trays containing coco peat was found to be suitable for plant growth. At the same time some of physiological parameters were optimized. Pogostemon Cablin plantlets when grow polythene sheet tunnel show best results where about 50 to 70 of relative humidity and 280 C temperature was maintained. It was also observed that plants were efficiently acclimatized after 30 days of incubation under polythene tunnels. The plants were well habituated in primary hardening condition and 8 plants could not survive in green house indicating very low morality rate in Pogostemon Cablin. 

The aqueous extract of Punica granatum L. peel was prepared by basic one-step liquid-liquid extraction. The extraction method involved partitioning 10% v/v water in methanol extract of the peel between ethyl acetate & 2% aqueous acetic acid. This specific extraction process increases the ellagic acid content by approximately double w/w. furthermore, the antioxidant activity is evaluated by the DPPH, radical scavenging assay, which tends to increase ED50 roughly by triple the value -µg/ml. these stability evaluations were measured under several conditions & temperatures, over a couple of months with successful results. 

The factors like humidity, sunlight, temperature fluctuations etc were all experimented during the stability test. Whereas, the acidity (pH) of the extract was the only loop-hole making it unstable in the aqueous or syrup (semi-solid) condition. Hence, the chemical constituent in the extract was stabilized when the extract was kept in amorphous, dried (powder) state. 

by Akanksha Samuel | Yogita Dobhal "Extraction, Stability & Storage of Punica Granatum L. Peel Extract" 

Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-4 , June 2018, 

Diabetes mellitus is one of the common metabolic disorder characterized by hyperglycemia due to defect in insulin secretion, insulin action or both and 2.8% of the population suffers from this disease throughout the world and it may cross 5.4% by the year 2025. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. It also a very prevalent disease affecting the citizens of both developed and developing countries. 

There are lots of synthetic chemical agents available in market to control and treat diabetic patients like sulfonylurea, biguanides, etc. but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents, many herbal plants with hypoglycaemic properties are known from across the world. Medicinal herbs as potential source of therapeutic aids have attained a significant role in health system all over the world for both humans and animals. 

India has about 45000 plant species and among them, several thousands have been claimed to possess medicinal properties. Herbal medicines have shown good clinical practice in the therapy of diabetic mellitus. In This present paper aims to review various plant species and their constituents, which have been used in the traditional system of medicine and have shown hypoglycaemic activity and various branded herbal formulations like D-400 tablet, Diasulin powder, Madurisht churna, Diabecon, Dia-care, etc. available in the market as antidiabetic remedies are also discussed. 

by Jayesh Gadhiya | Tanvay Jaithliya | Shubam Sehgal | Mrs. Neelam Somani "Herbals and its marketed formulations to treat Diabetes Mellitus (DM): An Overview" 

Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-3 , April 2018, 

Use of herbal medicines is propagating day-by-day and several tribes still rely upon this green treasure against their ailments. Being unfortunate to the environment, invasive plants species hold supreme remedies that are unique. Besides ethnoremedial uses they embrace anticancerous, antidiabetic, antimicrobial, antitubercular and other pharmacological attributes in them. In the present review, authors aimed to compile the segregated ethnomedicinal information of invasive plant species. 

The literature study revealed a significant ethnoremedial importance of invasive alien weeds that may serve to establish a ground for future researchers to explore in pharmacognostic field with safe and natural drug resource. 

by Shaiphali Saxena | P. B. Rao "Invasive Alien Plants: Valuable Elixir with Pharmacological and Ethnomedicinal Attributes" 

Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-3 , April 2018, 

International Journal, Pharmacognosy Journal