The basic rules in any good manufacturing practice GMP regulations postulate that the pharmaceutical manufacturer must maintain appropriate documentation and records. Documentation helps to build up a detailed interpretation of what a manufacturing function has done in the past and what it is doing now and, thus, it provides a base for planning what it is going...
Showing posts with label Pharmaceutics. Show all posts
Showing posts with label Pharmaceutics. Show all posts
Tuesday, 12 October 2021
Sunday, 12 September 2021
COVID 19
Team IJTSRD
September 12, 2021
0
Coronaviruses are important human and animal pathogens. At the end of 2019, a novel coronavirus was identified as the cause of a cluster of pneumonia cases in Wuhan, in the Hubei Province of China. It is rapidly spreading, resulting in an epidemic throughout china, followed by an increasing number of cases in other countries throughout the world. In February...
Thursday, 17 June 2021
A Review Solubility Enhancement and its Technique
Team IJTSRD
June 17, 2021
0
Solubility are often defined because the amount of solute dissolved during a solvent at certain conditions to yield a single ¬phase system. Solubility of active pharmaceutical ingredients is taken into account the foremost parameter to urge the most desired drug concentration generally circulation so as to realize the specified therapeutic effect. Poor aqueous...
Tuesday, 13 April 2021
Formulation Development and In Vitro Evaluation of Microsponge Drug Delivery System of Antifungal Drug
Team IJTSRD
April 13, 2021
0
A Microsponge Delivery System MDS is patented, highly cross linked, porous, polymeric microspheres that can entrap wide range of actives and then release them onto the skin over a time and in response to trigger. It is a unique technology for the controlled release of topical agents and consists of microporous beads, typically 10 25 microns in diameter, loaded...
Saturday, 3 April 2021
Piroxicam Nanostructured Lipid Carrier Drug Delivery System
Team IJTSRD
April 03, 2021
0
Objective Nanostructured lipid carrier NLC based topical gel of Piroxicam PXM was formulated with the aim of controlled release action and to reduce systemic side effect for the treatment of an arthritic condition. Methods NLCs developed using high pressure homogenization method and optimized using a 32 factorial design with response surface methodology using...
Saturday, 20 February 2021
Dyslipidemia Causes, Symptoms and Treatment
Team IJTSRD
February 20, 2021
0
Deaths that are caused due to coronary heart disease CHD is a major cause of deaths in most of the population. Even though the mortality rate has been reducing, dyslipidemia is the major known risk factor in pathogenesis of CHD. In this paper we review the role of dyslipidemia and lipid changes that occur in men and women at different stages. We discuss about...
Wednesday, 17 February 2021
Current Trends of “Nanotechnology” in Pharmaceutical
Team IJTSRD
February 17, 2021
0
Size reduction is one of most fundamental unit operation which is of prime importance in pharmacy. It helps in improving stability and bioavailability, reducing toxicity, enhancing release and providing better formulation opportunities for drug. In the recent trends, the drugs in nanometer size range have found to increase the performance in variety of dosage...
Tuesday, 17 November 2020
Microspheres and Kinds
Team IJTSRD
November 17, 2020
0
Background The concept of targeted drug delivery is meant for attempting to concentrate the drug within the tissues of interest while reducing the relative concentration of the medication within the remaining tissues.Now each day the recent development in new drug delivery systems plays a significant role in pharmaceutical industries. As a result, drug...
Sunday, 8 November 2020
Preparation and Evaluation of Immediate Release Tablets
Team IJTSRD
November 08, 2020
0
Background Tablet is that the preferred among all dosage forms existing today thanks to its convenience of self administration, compactness and simple manufacturing however in many cases immediate onset of action is required than conventional therapy. There are novel kinds of dosage form.The scenario of pharmaceutical drug delivery are expeditiously challenging,...
Sunday, 1 November 2020
Review on Osmotically Controlled Drug Delivery System
Team IJTSRD
November 01, 2020
0
Oral Osmotic Drug Delivery System is the new found delivery system of Novel Drug Delivery System. Oral Osmotic Drug Delivery System works on the principle of Osmosis and Osmotic Pressure for the pre planned and correct delivery of the drugs into the biological systems. Being independent of the pH and physiological conditions, it provides an upper hand into delivery...
Saturday, 17 October 2020
A Review on Solid Oral Dosage Forms with an Industrial Perspective for Process Validation
Team IJTSRD
October 17, 2020
0
Aim of the present review is to summarize various steps involved in process validation of the oral solid dosage forms in pharmaceutical industries. Oral solid dosage form such as tablets, capsules etc are widely used due to its easy administration and easily available to the market at affordable price. Validation it is an important part of current good manufacturing...
Thursday, 3 September 2020
Tablet Coating Not Only a Technical Work but also a Creative Art
Team IJTSRD
September 03, 2020
0
Tablet coating is technique which is use in different tablet formulation. It is well known technique to make a tablet protective and creative. Tablet coating is an art which develop creativity against different problems occurred in tablet manufacturing. Coating which was taken up towards its tablet formulation aim like controlled release, gastro retentive, gastro...
Wednesday, 26 August 2020
Quality by Design A Present to Future Perspective
Team IJTSRD
August 26, 2020
0
Quality by Design is the modern approach for quality of pharmaceuticals. This paper gives idea about the Pharmaceutical Quality by Design QbD and describes use of Quality by Design to ensure quality of Pharmaceuticals. The Quality by Design is described and some of its elements identified. Process parameters and quality attributes are identified for each unit...
Wednesday, 19 August 2020
Design and Development of Effervescent Floating Tablet Dapagliflozin
Team IJTSRD
August 19, 2020
0
The objective of the present study was to formulate and evaluate Effervescent Floating Tablet of Dapagliflozin for the treatment of antidepressant agent. Tablets were prepared by direct compression using directly compressible polymers such as HPMC K4M, and Carbopol 934 were evaluated for drug excipient compatibility, density, buoyancy test, swelling study, drug...
Saturday, 11 April 2020
Molecularly Imprinted Polymer Based Fluorescent Sensors A Promising Tool for Food and Environment Analysis
Team IJTSRD
April 11, 2020
0
Molecular imprinting technology MIT , also called as molecular template technology, it is a novel and innovative technology use in material chemistry, polymer chemistry, biochemistry, and other different approaches. Molecularly imprinted fluorescence sensor MIFs , a technique used to know the unique and selective capability of 3 dimensional cross linked polymer...
Thursday, 12 March 2020
A Review on Floating Drug Delivery System
Team IJTSRD
March 12, 2020
0
Floating drug delivery frameworks improves the medication bioavailability and patient consistence by expanding the gastric living arrangement time and controlling the medication discharge. In ongoing decades, there have been various endeavors to beat the boundaries like short gastric living arrangement times and eccentric gastric discharging times. In this...
Friday, 20 December 2019
Review on Microemulsion a Novel Approach for Antifungal Drug Delivery
Team IJTSRD
December 20, 2019
0
Microemulsion is an best candidates as novel drug drlivery system because of their shelf life and improve the drug solubilization with easy of preparation and administration. The term microemulsion refers to thermodynamically stable iostropically dispersion of two immisible liquid such as oil and water stabilized by interfacial film of surfactant molecule....
Wednesday, 18 December 2019
Illustrative Review on Radiopharmaceuticals
Team IJTSRD
December 18, 2019
0
Radiopharmaceutical is a key component involved in the field of nuclear medicine. It serves various purposes diagnostically and also serves with different diagnostic applications. Radioactive agents are employed in nuclear field for demonstration of high and exact localized radioactive effect in a particular target tissue. In recent years various amount of...
Friday, 6 December 2019
Formulation and Evaluation of Amlodipine Fast Dissolving Tablets
Team IJTSRD
December 06, 2019
0
Fast dissolving tablet is a new era for successful development of controlled release formulation along with various features to provide successful drug delivery. In the present study, an attempt was made to design and evaluate fast dissolving tablets of Amlodipine besylate, which is used commonly for the treatment of angina pectoris. The tablets were prepared...
Wednesday, 4 December 2019
Formulation and Evaluation of Cefixime Trihydrate Dispersible Tablets
Team IJTSRD
December 04, 2019
0
Therapeutically active ingredients like tablet and capsule are conventional pharmaceutical dosage forms for manufacture, storage and ensure dosage uniformity. However, this dosage forms like capsules and tablets, often present ingestion problems such as difficulty in swallowing for the debilitated patients, particularly for paediatric and geriatric populations....