International Journal of Trend in Scientific Research and Development

Polycystic ovary syndrome PCOS is a common endocrine and metabolic disorder in premenopausal women. Heterogeneous by its nature, PCOS is defined as combination of signs and symptoms of androgen excess and ovarian dysfunction in the absence of other specific diagnoses. The etiology of the syndrome remains unknown, but evidence suggests that PCOS might be a complex multigenic disorder with strong epigenetic and environmental influences, including diet and lifestyle factors. It affects 8 to 13 of reproductive aged women. Polycystic ovary syndrome PCOS is associated with hormonal, biochemical disturbance and adverse cosmetic, reproductive, metabolic, and psychological consequences, resulting in reduced health related quality of life HRQoL . The most recent international guidelines set lifestyle management as the cornerstone of the PCOS treatment. 

by Hridyanshi | R. K. Patil | Lovish Kansal "Polycystic Ovary Syndrome: A Review" 

Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-4 , June 2021, 

URL: https://www.ijtsrd.compapers/ijtsrd41134.pdf 

Paper URL: https://www.ijtsrd.commedicine/gynecology/41134/polycystic-ovary-syndrome-a-review/hridyanshi

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After 10 years of increasing conflict and violence in Syria, women face significant challenges associated with lack of adequate access to maternal health services, threatening their lives along with their immediate and long term health outcomes, among them miscarriage, which has been increasing dramatically. Our aim was to assess whether serum total antioxidant TAS capacity and total oxidant status TOS altered during first trimester pregnancies with vaginal bleeding and abdominal pain, and to investigate the accuracy of these biomarkers in the prediction of miscarriage. In this cross sectional study, A group of pregnant women with vaginal bleeding and abdominal pain n=29 served as patient group and a control group of healthy pregnancies n=30 were included. All of the participants in the two groups were matched for age and gestational age. All pregnant women were recruited from the Khaled Kendel hospital Sarmada, Syria, and Blood samples were collected at 6– 14 weeks from all participants for measurement of oxidative stress markers. The area under curve AUC was used to determine the predictive value of the oxidative stress indices. The mean TOS level was significantly P 0.05 higher in patients whereas mean TAS level was significantly P 0.05 decreased in patient group compared to the control group. The AUC of TOS and TAS were 0.611, 0.895, P= 0.115, 0.001 respectively. The cut off, sensitivity, and specificity of TAS were 0.98, 93.5 and 70.8 respectively. TAS can be used to discriminate between TM and the control subjects sensitivity= 0.956 P 0.0001 . Our analysis of patients presenting with threatened miscarriage in this study presents, imbalance in oxidative stress markers, we recommended supplementing of anti oxidants Throughout pregnancy. finally, Further high quality research in this area is warranted to confirm our results. 

by Ibrahim W. Hasani | Maism. Abdulrazak | Samer Kabba "Predictive Value of the Oxidative Stress Indices in Syrian Women with Threatened Abortion" 

Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-1 , December 2020, 

URL: https://www.ijtsrd.com/papers/ijtsrd35879.pdf

Paper URL : https://www.ijtsrd.com/medicine/gynecology/35879/predictive-value-of-the-oxidative-stress-indices-in-syrian-women-with-threatened-abortion/ibrahim-w-hasani

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