This was an interventional study which evaluated the effects of bromocriptine and carbegoline on prolactin, progesterone, luteinizing and follicle stimulating hormones in hyperprolactinaemic infertile female subjects in Orlu, South East Nigeria.Hyperprolactinaemic females who were attending Gynaecology Clinic at Imo State University Teaching Hospital IMSUTH Orlu participated in the study. The participants were divided into two groups. Group A 30 hyperprolactinaemic females were administered 1.25mg bromocriptine at night for the first one week 2.5mg at week two then 2.5mg twice daily for eighteen weeks. Group B 30 hyperprolactinaemic females were administered 0.25mg carbegoline twice weekly for eight weeks. Serum prolactin, progesterone, LH and FSH were assayed before and after treatment using enzyme linked immunesorbent assay ELISA kits. The significant difference between the mean values of prolactin, LH, FSH and progesterone, in the pre and post treatment with carbergoline and bromocriptine was determined by paired t test. Independent student t test was used to compare between the two treatments. P value 0.05 was considered as statistically significant.
by Ajaero, Oluchi Chinwe | Unekwe, Prince Chiazor | Ajaero, Nnaemeka Uchendu "Effects of Carbegoline and Bromocriptine on Prolactin, Progesterone, Luteinizing and Follicle Stimulating Hormones in Hyperprolactinaemic Infertile Women in Orlu, Nigeria" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5 , August 2021,
URL: https://www.ijtsrd.com/papers/ijtsrd45169.pdf
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