Vitamin D deficiency is widespread in both the pediatric and adult chronic kidney disease CKD population. CKD is characterized by dysregulation of vitamin D and mineral metabolism. Secondary hyperparathyroidism and its management puts patients with CKD at increased cardiovascular risk. Emergence of experimental and some clinical data suggesting beneficial effects of vitamin D on proteinuria, blood pressure, inflammation and cardiovascular outcomes has pushed it to the center stage of CKD research. Pediatric data on vitamin D dysregulation and its consequences are still in its infancy. Ongoing prospective studies such as Chronic Kidney disease in Children CKiD and the Cardiovascular Comorbidity in Children with CKD 4 C should help to delineate the evolution of disturbances in mineral metabolism and its adverse effects on growth, CKD progression and cardiovascular outcomes.
by Dr. Prafull Dawale | Neha Jain ""Vitamin D in Chronic Kidney Disease""
Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-5 , August 2019,
URL: https://www.ijtsrd.com/papers/ijtsrd26778.pdf
Paper URL: https://www.ijtsrd.com/medicine/other/26778/vitamin-d-in-chronic-kidney-disease/dr-prafull-dawale
call for paper health science, ugc approved engineering journal, social science journal
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