The brain is a delicate organ, and evolution built very efficient ways to protect it. Unfortunately, the same mechanisms that protect it against intrusive chemicals can also frustrate therapeutic interventions. Many existing pharmaceuticals are rendered ineffective in the treatment of cerebral diseases due to our inability to effectively deliver and sustain...
Showing posts with label Analytical Chemistry. Show all posts
Showing posts with label Analytical Chemistry. Show all posts
Saturday, 11 September 2021
Wednesday, 8 September 2021
Method Development and Validation for Estimation of Oral Hypoglycaemic Drug Dapagliflozinina Tablet Dosage form by the Employment of Rp HPLC
Team IJTSRD
September 08, 2021
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HPLC is a chromatographic technique employed in active compound chemistry and biochemistry to separate a mixture and substances with the goal of identifying, measuring, and purifying the different components of the mixture. Its a much better variety of column and traditional chromatography. The objective of the research work is to develop and validate a simple...
Monday, 6 September 2021
Stability Indicating HPLC Method Development A Review
Team IJTSRD
September 06, 2021
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High performance liquid chromatography is most powerful tools in analytical chemistry which assessing drug product stability. It is most accurate method for determining the qualitative and quantitative analysis of drug product. Forced degradation plays an important role in development of stability indicating analytical methodology. Stability indicating HPLC...
Sunday, 5 September 2021
Stability Indicating RP HPLC Method Development and Validation of Everolimus in Bulk and Pharmaceutical Dosage Form
Team IJTSRD
September 05, 2021
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Everolimus is semisynthetic derivative of sirolimus, which is isolated from Streptomyces hygroscopicus. A novel reversed phase high performnce liquid chromatography HPLC method for determination of the everolimus in the presence of degradation product or pharmaceutical excipients. Seperation was carried out using Cosmosil C18 250mm x 4. 6ID , column having particle...
Curcumin Based Nanotherapy of Cancer A Review
Team IJTSRD
September 05, 2021
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Cancer is the most prevalent disease not only in the United States but worldwide. The most representative polyphenol component extracted from the rhizomes of Curcuma long a known as turmeric is curcumin. The therapeutic benefits of curcumin have been demonstrated in multiple chronic diseases inflammation, arthritis, metabolic syndrome, liver disease, obesity,...
Thursday, 10 December 2020
Application of Hydrotrophy in HPLC Hydrotrophic Solution, A Novel Cost Effective and Eco Friendly Mobile Phase for Solubilization of Poorly Water Soluble Drugs
Team IJTSRD
December 10, 2020
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Hydrotrophy is a unique molecular phenomenon that posses the ability to increase the solubility of sparingly soluble and poorly soluble drugs in water. A hydrotrophic solution can be defined as adding a solute, that is Hydrotrope, eg urea to the primary one solvent and is used as mobile phase for HPLC. High solubility, easy availability, cost effectiveness,...
Thursday, 24 September 2020
Review Article on Valsartan
Team IJTSRD
September 24, 2020
0
A simple, sensitive, rapid and reproducible HPLC method has been developed and validated for Calibration determination of Valsartan in bulk and in pharmaceutical formulation by applying Quality intentionally. For development of HPLC method for Valsartan various trials are performed by using Design Expert software by applying 3 level factorial designs. Quantitative...
